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Li, H., Kanamori, Y., Nita, A., Maeda, A., Zhang, T., Kikuchi, K., Yamada, H., Toyomoto, T., Saleh, M.F., Niimura, M., Hinokuma, H., Shimoda, M., Ikeda, K., Suzuki, M., Komohara, Y., Kurotaki, D., Sawa, T., and Moroishi, T.
Hippo pathway controls biopterin metabolism to shield adjacent cells from ferroptosis in lung cancer.
EMBO Rep. 26, 4124-4152 (2025).
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Yamane, T., Kanamori, Y., Sawayama, H., Yano, H., Nita, A., Ohta, Y., Hinokuma, H., Maeda, A., Iwai, A., Matsumoto, T., Shimoda, M., Niimura, M., Usuki, S., Yasuda-Yoshihara, N., Niwa, M., Baba, Y., Ishimoto, T., Komohara, Y., Sawa, T., Hirayama, T., Baba, H., and Moroishi, T.
Iron accelerates Fusobacterium nucleatum-induced CCL8 expression in macrophages and is associated with colorectal cancer progression.
JCI insight 7, e156802 (2022).
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Moroishi, T.
ANXious for YAP.
Nat. Chem. Biol. 17, 750–751 (2021).
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*Muto, Y., *Moroishi, T., Ichihara, K., Nishiyama, M., Shimizu, H., Eguchi, H., Moriya, K., Koike, K., Mimori, K., Mori, M., Katayama, Y., and Nakayama, K.I. [*Equal contribution]
Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.
J. Exp. Med. 216, 950-965 (2019).
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Moroishi, T., Hayashi, T., Pan, W.W., Fujita, Y., Holt, M.V., Qin, J., Carson, D.A., and Guan, K.L.
The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell 167, 1525-1539 (2016).
-- HIGHLIGHTED IN "Dev. Cell 39, 635-637 (2016)" --
-- HIGHLIGHTED IN "Cancer Discov. 7, OF8 (2017)" --
-- HIGHLIGHTED IN " J. Thorac. Dis. 9, 1748-1751 (2017)" --
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Moroishi, T., Park, H.W., Qin, B., Chen, Q., Meng, Z., Plouffe, S.W., Taniguchi, K., Yu, F.X., Karin, M., Pan, D., and Guan, K.L.
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
Genes Dev. 29, 1271-1284 (2015).
*Moroishi, T., *Hansen, C.G., and Guan, K.L.
The emerging roles of YAP and TAZ in cancer
Nat. Rev. Cancer 15, 73-79 (2015). [*Equal contribution]
*Hansen, C.G., *Moroishi, T., and Guan, K.L. [*Equal contribution]
YAP and TAZ: a nexus for Hippo signaling and beyond.
Trends Cell Biol. 25, 499-513 (2015).
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Moroishi, T., Nishiyama, M., Takeda, Y., Iwai, K., and Nakayama, K.I.
The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.
Cell Metab. 14, 339-351 (2011).
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東京科学大学 総合研究院
難治疾患研究所 病態制御科学研究部門
細胞動態学分野
〒113-8510 東京都文京区湯島1-5-45 M&Dタワー22F
(受付) TEL: 03-5803-4821
FAX: 03-5803-4683
E-MAIL: moroishi.toshiro [at] tmd.ac.jp
Division of Cellular Dynamics
Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo
1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, JAPAN
(Desk) TEL: +81-3-5803-4821
FAX: +81-3-5803-4683
E-MAIL: moroishi [at] kumamoto-u.ac.jp